img

Advanced Clinical Quality Management & Data Integrity for Investigational Medicinal Products in Clinical Trials

Course Description

This intensive two-day live virtual training provides an in-depth exploration of Clinical Quality Management Systems (QMS) and Data Integrity as they apply to an Investigational Medicinal Product (IMP). Designed for professionals supporting complex clinical development programs, the course focuses on how quality is designed, implemented, and sustained across the product-to-patient lifecycle, in alignment with current ICH E6(R3) Quality by Design (QbD) expectations.

Led by Jon Prigge, Ph.D., Clinical Quality Leader and Data Integrity & GxP Compliance Specialist, this training emphasizes systems-based thinking and practical application. Participants will learn how effective quality system design supports reliable data, inspection readiness, and patient safety—particularly within hybrid paper and electronic environments that continue to challenge modern clinical operations.

The course places Data Integrity at the center of clinical validity, moving beyond checklist compliance and “human error” narratives to examine systemic contributors to quality outcomes. Through instructor-led discussion and interactive exercises, attendees will strengthen their ability to identify quality vulnerabilities, evaluate documentation integrity, and apply proportionate oversight strategies across global clinical trials.

By the conclusion of the training, participants will have a clearer understanding of how QMS design, Data Integrity, and risk-aware oversight intersect in real-world clinical research—and how to translate regulatory expectations into sustainable, inspection-ready practices.

Course at a Glance

2-Day Live Virtual Workshop
2 Full Days of Interactive Learning

Intensive, instructor-led sessions

July 15-16,2026

Upcoming Virtual Workhop

9:00 AM - 4:00 PM EST

Small-group, live instructor-led sessions

Price : $1995.00 USD
location Created with Sketch Beta.
Location:

Participate from anywhere with stable internet

certificate-ribbon-solid
Certificate of Completion from CRTA

Recognized professional credential

Faculty Director: Jon Prigge
Limited Seats - Secure Your Spot Early!

Learning Objectives

By the end of this course, participants will be able to:

  • Apply systems-based quality thinking to strengthen QMS design and oversight for IMPs
  • Identify and address Data Integrity vulnerabilities across paper, hybrid, and electronic environments
  • Move beyond “human error” to evaluate systemic contributors to clinical quality issues
  • Apply proportionate, risk-aware oversight strategies aligned with ICH E6(R3)
  • Strengthen audit and inspection readiness through improved documentation integrity and technical compliance

Who Should Attend

  • Quality Assurance and Quality Control professionals supporting clinical trials
  • Clinical Research Associates and Clinical Research Coordinators
  • Scientific Leads and Principal Investigators
  • Regulatory Affairs professionals
  • Clinical Operations team members
  • Project Managers and Clinical Trial Managers
  • Professionals preparing for audits/inspections, or expanded quality oversight responsibilities

Course Outline

Course Modules

Module 1

Clinical quality foundations and the evolving regulatory landscape

Module 2

Quality oversight across the technical lifecycle of the IMP

Module 3

Data Integrity in practice: ALCOA+, hybrid systems, and documentation integrity

Module 4

Core components of an effective and scalable clinical QMS

Module 5

Quality risk thinking and proportionate oversight strategies aligned with ICH E6(R3)

Module 6

Moving beyond human error: identifying systemic contributors to quality issues

Module 7

Audit and inspection readiness in remote, digital, and hybrid environments

The course progresses from regulatory and system fundamentals to applied decision-making and inspection-focused considerations, reinforcing how quality concepts translate into real-world clinical oversight.

Interactive Activities

This course features live, instructor led interactive activities designed to reinforce key concepts and support real world application of clinical quality and Data Integrity principles. Activities emphasize critical thinking, scenario analysis, and systems based evaluation, rather than prescriptive or tool driven exercises.

Planned activities include:

  • Data Integrity & Hybrid Systems Analysis: Participants will examine realistic clinical workflows that span paper, hybrid, and electronic environments to identify where Data Integrity may be compromised and how system design influences data reliability.

  • Systemic Quality Gap Identification: Through applied quality scenarios, participants will practice identifying system-level contributors to GxP issues, focusing on process design, oversight models, and cross-functional interfaces rather than “human error.”

  • Proportionate Oversight Decision Scenarios: Participants will evaluate oversight approaches aligned with ICH E6(R3), discussing how to apply proportionate, risk-aware quality strategies in complex and resource-constrained clinical settings.

The course concludes with a facilitated synthesis discussion, connecting QMS design, Data Integrity, and inspection readiness to reinforce how these concepts work together in realworld clinical operations.

Jon Prigge, B.S., Ph.D.
Faculty Director’s Bio:

Jon Prigge, B.S., Ph.D.

Clinical Quality Leader | Data Integrity & GxP Compliance Specialist | IMP Quality Strategist | Educator

Jon Prigge, Ph.D. is a clinical quality professional and educator specializing in the design and implementation of scalable Quality Management Systems and technical oversight of Investigational Medicinal Products. With nearly 20 years of experience across regulated research and development environments, he brings a practical, systems-based perspective to clinical quality and compliance.

Dr. Prigge combines deep scientific expertise with hands-on quality leadership to help organizations build inspection-ready processes that support reliable data and patient safety. His experience includes supporting the transition of products from preclinical development into clinical research, as well as contributing to quality systems associated with FDA-licensed products, providing insight into lifecycle quality and regulatory expectations.

His background also includes conducting and supporting audits within NIH-supported research programs, offering direct experience with compliance, documentation integrity, and quality oversight in federally funded clinical and translational research. He has additionally supported quality activities associated with a key antiviral maintained in the U.S. national stockpile, reinforcing his understanding of high-impact, public-health-focused product oversight.

Dr. Prigge has developed and delivered advanced GxP and clinical quality training for academic institutions, government programs, and industry teams, with a focus on Data Integrity, systemic root cause analysis, and sustainable quality culture. Known for an engaging and applied teaching style, he translates complex regulatory concepts into clear, actionable practices for clinical research professionals.

Become Our Faculty Director Today

Be part of a global network of virtual and in-person workshops

Global Pharma companies and CROs employing our graduates

Global Pharma companies and CROs
employing our graduates